Louisville vs Notre Dame Odds and Preview: Cardinals are Home Underdogs In Marquee Matchup

The undefeated Louisville Cardinals are gearing up for a prime-time matchup against the Notre Dame Fighting Irish on Saturday night. Kickoff is set for 7:30 p.m. ET. To make the action even better, you can claim several Kentucky sports betting welcome bonuses with our promo codes.

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Louisville vs Notre Dame Preview

Louisville Cardinals: Are The Cards For Real?

The Louisville Cardinals are off to an impressive start under head coach Jeff Brohm. The former Louisville quarterback has led his team to a 5-0 record, and the Cardinals find themselves ranked in the AP poll at No. 25. Louisville’s wins have come against Georgia Tech, Murray State, Indiana, Boston College, and NC State. Needless to say, this matchup against No. 10 Notre Dame will be their toughest test yet.

The Cardinals have had an extra day to prepare, as they last played on Friday, Sept. 29. They took down NC State on the road 13-10 in a game that was ugly from start to finish. Although the Cardinals won the game, they committed 10 penalties and turned the ball over three times. They will have to clean things up if they are hoping to take down the Fighting Irish.

Oddsmakers are expecting a close game this weekend, as Notre Dame is favored by six points on most sports betting platforms. If the Cardinals are going to pull off the upset, they are going to have to take care of the ball. QB Jack Plummer has thrown six interceptions in five games, while Notre Dame’s QB Sam Hartman has yet to throw a pick. Notre Dame’s defense is among the best in the country, so preventing turnovers will be key.

Notre Dame Fighting Irish: Another Test

Notre Dame enters this game with a 5-1 record. After steamrolling their first four opponents, the Fighting Irish have played back-to-back nail-biters against Ohio State and Duke. They fell short against the Buckeyes, but picked up a big road win last week against the Blue Devils. This team is more battle-tested than the Cardinals, but the emotional highs and lows of the past two weeks could put them in a vulnerable spot here.

As mentioned, Notre Dame QB Sam Hartman has yet to throw an interception this season. In fact, Hartman holds the Notre Dame school record for most pass attempts without an interception to start a season. The Cardinal defense has forced five interceptions on the year, and if they are able to pick off Hartman, it could provide a big momentum swing. But the Cardinals also have to try to slow down RB Audric Estime, who leads the nation with 672 rushing yards. He’s also found the end zone seven times on the ground.

Louisville Cardinals vs Notre Dame Fighting Irish Prediction

After scoring 41+ points in each of their first four games, the Irish have scored just 14 and 21 points in their last two games. With a big rivalry game against USC looming next week, look for Notre Dame to tune up its offense in this one. Hartman and Estime are among the best QB/RB duos in the country, and if they get going early, Louisville’s offense may have a tough time keeping up. Look for the Irish offense to come out swinging, while their elite defensive unit holds Plummer and company in check. Irish win 34-20.

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