Week 6 of the NFL season is here, and the 14-game schedule features a number of intriguing matchups and divisional showdowns.
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Week 6 NFL odds: Another London matchup on tap with Bears-Jaguars
Following is the complete NFL Week 6 schedule, with kickoff times, early-week sportsbook consensus point spreads and totals and a quick thought on each of the 14 contests, beginning with …
San Francisco 49ers (-3.5, 49) at Seattle Seahawks, 8:15 p.m. ET Thursday (Amazon Prime Video)
The Niners (2-3) have won five straight (4-1 ATS) in this NFC West rivalry, including 31-13 and 21-13 victories in their last two visits to the Pacific Northwest.
Jacksonville Jaguars vs. Chicago Bears (-2.5, 44.5) in London, 9:30 a.m. Sunday (NFL Network)
With 11 all-time games in the UK, the Jags (1-4) are London’s de facto NFL team, and they’ve gone 6-5 in those contests, including a 3-1 record over the last three seasons.
Arizona Cardinals at Green Bay Packers (-5, 49.5), 1 p.m. Sunday
Kyler Murray and the Cards (2-3) are coming off an impressive upset win over the host 49ers, but that will be tough to duplicate as Jordan Love and the Pack have won three of their last four to move to 3-2.
Indianapolis Colts (-1, 43) at Tennessee Titans, 1 p.m. Sunday
Indy (2-3) won both games in this AFC South series a season ago, but the Titans (1-3) had won five straight prior to that.
Houston Texans (-7, 38) at New England Patriots, 1 p.m. Sunday
Rookie QB Drake Maye reportedly will get his first career start for the Pats (1-4), who have dropped six straight home games, dating back through Week 9 of last season.
Tampa Bay Buccaneers (-3.5, 41.5) at New Orleans Saints, 1 p.m. Sunday
The Bucs (3-2) have won three of the last four meetings in this NFC South series, and the host Saints (2-3) likely will be without starting QB Derek Carr, who suffered an oblique injury in Monday night’s loss in Kansas City.
Cleveland Browns at Philadelphia Eagles (-8.5, 43.5), 1 p.m. Sunday
Philly (2-2) comes out of its bye as the largest Week 6 favorite, hosting struggling QB Deshaun Watson (league-worst 21.0 QBR) and the 1-4 Browns.
Washington Commanders at Baltimore Ravens (-6.5, 52), 1 p.m. Sunday
This is a fascinating regional matchup pitting 2023 NFL MVP Lamar Jackson and the 3-2 Ravens against current Offensive Rookie of the Year favorite Jayden Daniels and the 4-1 Commanders.
Los Angeles Chargers (-3, 35.5) at Denver Broncos, 2:05 p.m. Sunday
The Broncos (3-2) have won three straight this season behind one of the league’s best defenses and are 9-1 in their last 10 home games against the AFC West-rival Bolts.
Pittsburgh Steelers (-3, 36.5) at Las Vegas Raiders, 4:05 p.m. Sunday
It’s the 3-2 Steelers visiting the 2-3 Raiders, and it wouldn’t be shocking to see new starting QBs for each team in Russell Wilson and Aidan O’Connell.
Detroit Lions (-3.5, 52.5) at Dallas Cowboys, 4:25 p.m. Sunday
Detroit (3-1) is laying a field goal on the road against 3-2 Dallas in a rematch of the Cowboys’ controversial 20-19 Week 17 win last December.
Atlanta Falcons (-6, 47.5) at Carolina Panthers, 4:25 p.m. Sunday
The Falcons (3-2) have beaten the Panthers (1-4) in 12 of their last 17 head-to-head meetings, but they’ve split in each of the last four seasons.
Cincinnati Bengals (-3.5, 48.5) at New York Giants, 8:20 p.m. Sunday (NBC, Peacock)
You would never know just looking at this Sunday Night Football point spread, but Daniel Jones and the 2-3 Giants have won twice as many games as Joe Burrow and the 1-4 Bengals.
Buffalo Bills (-2.5, 41) at New York Jets, 8:15 p.m. Monday (ESPN)
It’ll be interesting to see how the Jets (2-3) look after firing head coach Robert Saleh on Tuesday as they host Josh Allen and the AFC East-leading Bills (3-2), who have dropped two straight after a 3-0 start.
Week 6 NFL odds: Claim your sports betting bonuses, top online sportsbook promotions
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